기관회원 [로그인]
소속기관에서 받은 아이디, 비밀번호를 입력해 주세요.
개인회원 [로그인]

비회원 구매시 입력하신 핸드폰번호를 입력해 주세요.
본인 인증 후 구매내역을 확인하실 수 있습니다.

회원가입
서지반출
Effects of Motor Learning on Motor Function and Synaptic Plasticity of Cerebellar Injuries
[STEP1]서지반출 형식 선택
파일형식
@
서지도구
SNS
기타
[STEP2]서지반출 정보 선택
  • 제목
  • URL
돌아가기
확인
취소
  • Effects of Motor Learning on Motor Function and Synaptic Plasticity of Cerebellar Injuries
  • 운동학습이 소뇌손상 후 운동능력 및 신경연접 가소성에 미치는 영향
저자명
김기도
간행물명
한국보건기초의학회지KCI
권/호정보
2020년|13권 2호(통권31호)|pp.106-111 (6 pages)
발행정보
한국보건기초의학회|한국
파일정보
정기간행물|ENG|
PDF텍스트(0.97MB)
주제분야
보건학
원문 미리보기는 1페이지만 제공 됩니다. 전체 페이지 보기를 원하실 경우 다운로드열람하기를 이용해 주세요.
서지반출

영문초록

The purpose of this study was to investigate the effects of motor learning on motor function and synaptic plasticity in rats with cerebellar injuries caused by harmaline. The test subjects were divided into three groups, with 15 rats assigned to each group. Group I was a normal control group (induced by saline); Group II was a experimental control group (cerebellar injuries caused by harmaline); Group III was the group that received motor learning after being cerebellar injured by harmaline. In the motor function test, the outcome of group II was significantly lower than that of group III (p<0.001). In the histological findings, the dendrites and nuclei of the cerebellar neurons of the experimental groups were severely damaged. While group III showed a decrease in degeneration of the cerebellar neurons in comparison. The immunohistochemistric response of synaptophysin in the cerebellar cortex was lower in the experimental groups than group I. However group III’s expression of synaptophysin was higher than group II. In electron microscopy findings, the experimental groups showed degeneration of the Purkinje cell. These result suggest that improved motor function by motor learning, after harmaline induced cerebellar injuries, is associated with dynamically altered expression of synaptophysin in the cerebellar cortex and that it is related with synaptic plasticity.

목차

INTRODUCTION
METHODS
RESULTS
DISCUSSION
CONCLUSION

구매하기 (3,000)