Objectives: The purpose of this study is to analyze the trend of single-case studies within Korean family therapy research and to suggest implications for future research. Methods: For this purpose, we searched 77 articles applying single-case studies that had been published in 『the Journal of Korean Association of Family Therapy』 and 『Family and Family Therapy』 between 1993 and 2017. We conducted frequency analysis and keyword network analysis by using the technique of text mining in the Textom program and also performed literature review on the articles. Results: First, although the number of single-case study articles published in the journals is steadily increasing, the proportion of single-case study articles as compared to the total articles is on the whole declining. Second, the frequency of the keywords appearing in the contents of single-case studies varies from 1993 to 2017 by 5 years. In the early days, there were no obvious keywords to be noted. Recently, ‘change’, ‘client’, ‘research’ and ‘experience’ have been emphasized. Third, the overall research trend of single-case studies is dominated by case studies with qualitative research characteristics. Conclusions: This study has the significance of exploratory basic work to contribute to the establishment of proper direction and activation of single-case studies in the Korean family therapy research field, as well as to the further establishment of evidence–based practice linking research and clinical engagement.