기관회원 [로그인]
소속기관에서 받은 아이디, 비밀번호를 입력해 주세요.
개인회원 [로그인]

비회원 구매시 입력하신 핸드폰번호를 입력해 주세요.
본인 인증 후 구매내역을 확인하실 수 있습니다.

회원가입
서지반출
흰쥐의 위산(胃酸)분비에 대한 고장(高張)포도당용액의 영향
[STEP1]서지반출 형식 선택
파일형식
@
서지도구
SNS
기타
[STEP2]서지반출 정보 선택
  • 제목
  • URL
돌아가기
확인
취소
  • 흰쥐의 위산(胃酸)분비에 대한 고장(高張)포도당용액의 영향
  • Effects of hypertonic glucose solution on acid secretion of rat stomach
저자명
김혜영(H.Y. Kim),조태순(T.S. Cho),홍사석(S.S. Hong)
간행물명
대한약리학잡지
권/호정보
1976년|12권 1호(통권18호)|pp.57-62 (6 pages)
발행정보
대한약리학회|한국
파일정보
정기간행물|KOR|
PDF텍스트(0.21MB)
주제분야
의약학
서지반출

영문초록

Using modified technique of Schmidt et al, as described previously (Korean J. Pharmacol 9 : 17, 1973), the stomach of female rats were perfused with physiological saline under urethane anesthesia. The acid-secretory response of the perfused stomach to i.v. hypertonic glucose (50%), casein hydrolysate (20%) or saline (6%) solution were studied with or without histamine or methacholine stimulation. A significant decrease of acid secretion from the rat stomach was induced by i.v. hypertonic glucose or saline solution. The histamine-stimulated acid secretion was also decreased by simultaneous administration of the hypertonic glucose or saline. However, methacholine-stimulated acid response was not affected by the hypertonic glucose. Intravenous infusion of 20% casein hydrolysate solution resulted in an increase in acid output from the stomach under histamine stimuli. These results lead to the conclusion that the inhibitory responses of acid secretion due to i.v. hypertonic glucose solution are brought through the effect of histaminergic, not cholnergic mechanism(s) in the gastric secretion.

구매하기 (3,000)