Purpose: Some studies have reported that Autogenous demineralized dentin matrix (ADDM) granules which were demineralized with
2% HNO₃ for 20 minutes have osteoinduction and osteoconduction. The aim of this study is finding out the proper demineralization
time for using ADDM block as the graft material in comparison previous studying that evaluate the proper demineralization time ADDM
granules which were demineralized with 2% HNO₃.
Materials and Methods: The enamel of crown was removed and the dentin was shaped as a rectangular parallelepiped for making
tooth block (8×8×5 mm). In tooth-blocks, 1 mm diameter holes were formed every 1 mm intervals. Each tooth-blocks were demineralized
in 2% HNO₃ solution for 1, 2, 3 hours. The change of weight, radiological density and minerals (Ca, P) were measured.
Results: This result has showed that ADDM block which was demineralized by 2% HNO₃ is needed to have 2 hours demineralization
time. But when applying this to clinical cases, we should consider that it is needed to take subdivided times for the better efficient, economical
and stable demineralization time and histological studies through additional animal test.
Conclusion: These results of ADDM blocks were compared with the results of ADDM granules that were already confirmed to evaluate
proper demineralization time for using the ADDM block as graft material. (JOURNAL OF DENTAL IMPLANT RESEARCH