기관회원 [로그인]
소속기관에서 받은 아이디, 비밀번호를 입력해 주세요.
개인회원 [로그인]

비회원 구매시 입력하신 핸드폰번호를 입력해 주세요.
본인 인증 후 구매내역을 확인하실 수 있습니다.

회원가입
서지반출
Bone inducing effect by recombinant human bone morphogenetic protein-2 and collagen carrier in maxillary sinus of the rabbit
[STEP1]서지반출 형식 선택
파일형식
@
서지도구
SNS
기타
[STEP2]서지반출 정보 선택
  • 제목
  • URL
돌아가기
확인
취소
  • Bone inducing effect by recombinant human bone morphogenetic protein-2 and collagen carrier in maxillary sinus of the rabbit
  • 가토 상악동에서의 rhBMP-2와 콜라겐 운반체에 의한 골유도 효과
저자명
Hyo-Jeong Son,Yeong-Wook Kim,Hong-Jun Hwang,Hyoun-Chull Kim,Sang-Chull Lee,Seung-Hwan O,Jingo Kusukawa,Rhuichiro Tanoue
간행물명
Journal of Dental Implant Research
권/호정보
2011년|30권 2호(통권36호)|pp.115-122 (8 pages)
발행정보
대한치과이식임플란트학회|한국
파일정보
정기간행물|ENG|
PDF텍스트(0.37MB)
주제분야
의약학
원문 미리보기는 1페이지만 제공 됩니다. 전체 페이지 보기를 원하실 경우 다운로드열람하기를 이용해 주세요.
서지반출

영문초록

Purpose: The aim of this study was to evaluate the bone inducing effects on the maxillary sinus of rabbits using the first commercial rhBMP-2 in South Korea and to investigate the influence of supplementation with collagen sponges. Materials and Methods: Two circular windows (diameter, about 4 mm) was formed in the nasal bone of rabbit The preparated maxillary sinuses were filled with collagen sponges (TerudermisⓇ) alone in three groups. In the other three groups, the preparated maxillary sinuses were filled with collagen sponges (TerudermisⓇ) acompanied with rhBMP-2, 20 μg (0.5 mg/cm3). Animals were sacrificed at 2, 4 and 8 weeks. The experimental sections were stained with hematoxylin and eosin for histopathologic analysis. Results: After 2 weeks, newly formed woven bone was seen. At four weeks, the bone was more mature than at 2 weeks. After 8 weeks, additional new bone formation was seen and much of the woven bone in the augmented space had been replaced by lamellar bone and fatty tissue. In the rhBMP-2 treated groups, for four weeks, histological findings were similar to those in the experimental group without rhBMP-2. In the rhBMP-2, however, significant bone regeneration ability was seen. Conclusion: In this study, we showed that the rhBMP-2 used in this experimental model was able to induce bone regeneration when combined to the carriers. BMPs have potency as alternatives to bone graft and accelators of the new bone formation. Concerned with this study, we thought further investigation are needed about the effective dose and comparative study of the effect of rhBMP-2 on autogenous bone graft, allograft, xenograft, and artificial bone graft or additional study of application of stem cells. (JOURNAL OF THE KOREAN ACADEMY OF IMPLANT DENTISTRY 2011;30(2):115-122)

목차

INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSIONS
CONCLUSION
REFERENCES

구매하기 (3,000)