The purpose of this descriptive study was for understanding causes of how general characteristics, major satisfaction and job-seeking stress impact on career preparative behavior in of senior nursing students. The study target were the convenience sampled 205 senior nursing students in 4 university. Data were analyzed by descriptive statistics, t-test, ANOVA, Scheffe test, Person's correlation coefficients, and Hierarchical multiple regression analysis using SPSS 23.0 program. According to the study result, the level of carrier preparation behavior was positively correlated with levels of major satisfaction(γ =.28∼.39 p<.001), and job-seeking stress(γ=16, p<.05) and its power of explanation reveals as 24%. In the nursing student's general characteristics, their academic records and school satisfaction level impact to its career preparative behavior. Therefore, we need to develop a program to increase its satisfaction level of academic achievement, school life, and their major study in order to manage the career preparative behavior effectively in senior nursing students.