기관회원 [로그인]
소속기관에서 받은 아이디, 비밀번호를 입력해 주세요.
개인회원 [로그인]

비회원 구매시 입력하신 핸드폰번호를 입력해 주세요.
본인 인증 후 구매내역을 확인하실 수 있습니다.

회원가입
서지반출
DENA와 CCl4를 투여한 흰쥐의 간에 대한 수종 한약재의 항암 및 항산화활성
[STEP1]서지반출 형식 선택
파일형식
@
서지도구
SNS
기타
[STEP2]서지반출 정보 선택
  • 제목
  • URL
돌아가기
확인
취소
  • DENA와 CCl4를 투여한 흰쥐의 간에 대한 수종 한약재의 항암 및 항산화활성
  • The Antioxidant Activity of the Several Medicinal Plants against Diethylnitrosamine (DENA) and CCl4 Treated Liver Injury in Rats
저자명
윤중식, 김정상
간행물명
한국보건기초의학회지KCI
권/호정보
2009년|2권 2호(통권4호)|pp.132-138 (7 pages)
발행정보
한국보건기초의학회|한국
파일정보
정기간행물|KOR|
PDF텍스트(0.18MB)
주제분야
보건학
원문 미리보기는 1페이지만 제공 됩니다. 전체 페이지 보기를 원하실 경우 다운로드열람하기를 이용해 주세요.
서지반출

국문초록

영문초록

The study was aimed to investigate the anticancer and antioxidant activity of several medicinal plants on DENA and CCl4 treated Rats. The rats were divided into three groups or four groups?: normal group (Nor), cirrhosis and hepatic cancer inducing control group (Con), and medicinal plants extract 320 mg/kg/day (Exp) administered groups to Con. The body weight decreased significantly in Con compared with the Nor group. The weight of liver/100 g body weight decreased significantly (p<0.05) in Con, but increased in Exp compared with Nor group. The ratio of neutrophil significantly increased (p<0.05) in the Con and Exp compared with Nor group. The activities of transaminase, alkaline phosphatase (ALP), and lactacte dehydrogenase (LDH) were significantly increased (p<0.05) in the Con compared with Nor group, but decreased in the Exp compared with Con group. Alpha fetoprotein (AFP) increased the most in the Con compared to Exp group. The results of light microscopical observation, a number of hepatocytes were damaged in the Con compared with Nor group and medicinal plants extract administerd groups. The number of hepatic p53 positive cells was reduced in the Exp compared with Con group. Based on these results, it is suggested that administration of several medicinal plants extract protective liver from carcinogenesis and oxidative stress induced by DENA and CCl4 in rats.

목차

서 론
재료 및 방법
결과 및 고찰
결 론
참고문헌

구매하기 (3,000)
추천 연관논문